Biology News
Differential pharmacology and clinical utility of sonidegib in advanced basal cell carcinoma - Dove Medical Press


Dove Medical Press
Abstract: Patients suffering from advanced basal cell carcinoma (BCC) have very limited treatment options. Sonidegib selectively inhibits the growth of Hedgehog pathway-dependent tumors and can treat locally advanced BCC patients who are not candidates ...

Metabolism regulates lymphangiogenesis - Nature.com


Nature.com
Wong et al. report that metabolism — more specifically, fatty acid β-oxidation (FAO) — promotes lymphatic development. They found that FAO is high in lymphatic endothelial cells (LECs; which line lymph vessels) and that inhibition or LEC-specific ...

Size matters when it comes to keeping blood sugar levels in check - Medical Xpress


Medical Xpress
"We found that when DRP1 activity in the neurons was missing, these neurons were more sensitive to changes in glucose levels," said Diano, who is also a member of the Program in Integrative Cell Signaling and Neurobiology of Metabolism and the director ...

Chronic Alcohol Use and Sleep Homeostasis: Risk Factors and Neuroimaging of Recovery - Psychiatric News


Psychiatric News
Porkka-Heiskanen T, Kalinchuk AV: Adenosine, energy metabolism and sleep homeostasis. Sleep Med Rev 2011; 15:123–135 CrossRef. 3. Tononi G, Cirelli C: The Neurobiology of Sleep, in Neurobiology of Mental Illness, 4th ed. Edited by Charney DS, ...

Meet your ancestor: Sea creature marks 'earliest' step in evolution - Irish Times


Irish Times
It might have a face only a mother could love but this bag-like sea creature ranks as our earliest known human ancestor. It looks fearsome but in fact probably measured no more than a millimetre across. Even so it lies on the evolutionary pathway that ...
The Guardian
Vocativ
BBC News

Team reports new role for enzyme involved in bacterial metabolism - Phys.Org


Phys.Org
"Many of the core metabolic pathways are shared across widely diverse branches of life, and fundamental understanding of the enzymes involved is a central effort of cell biology and biochemistry," he says. "This basic knowledge is also critical for ...

Bilirubin Metabolism Pathway

Metabolism Course Notes
Canada

Text and illustrations on human metabolism. Covers pathways, hormonal regulation, and some discussion of medical correlations such as diabetes and ...

Metabolism - Clinical And Experimental
United States

metabolism promotes excellence in research by publishing high-quality original research papers, fast-tracking cutting-edge papers, research brief reports, mini-reviews, and other ...

kidshealth - Metabolism Basics
United States

Our bodies get the energy they need from food through metabolism, the chemical reactions in the body's cells that convert ...

Ingenuity Pathways Analysis
United States

Offer a web-based mammalian biology knowledgebase and analysis tool used for drug discovery and genomic data analysis.

United States

Guide to bioinformatic resources and annotations from San Francisco State University.

KEGG
Japan

KEGG Regulatory Pathways -- a collection of graphical pathway maps, ortholog group tables, and molecular catalogs. Includes a few signaling ...

Pathway Tools
United States

Predict metabolic pathways from genomes and graphically depict pathways. Visualize gene expression data on a metabolic pathway map. Generate a ...

BioBase
Germany

Provides expert level, human-curated databases for drug discovery and life science researchers for gene expression, regulation and transcription pathway discovery.

Sea Otter Metabolism
United States

Find information on how one of the species thermoregulatory adaptations is a high metabolism. Includes references cited and information on ...

ProteinLounge
United States

Bioinformatics portal which integrates protein information and many databases and research tools useful for researchers and students. Subscription based service.

Liver Metabolism
United Kingdom

Flow chart of liver metabolism. Mousing over the chart will display explanations of pathways and enzyme reaction in pop-up windows ...

Ariadne Genomics Inc.
United States

Software for biological pathways visualization and analysis, functional interpretation of genetic information.

General Overview of the Major Metabolic Pathways
Portugal

A survey of human metabolism, written for undergraduates in the Health Sciences from a chemist's point of view. Includes profile ...

Signal Transduction - Receptors, Mediators and Genes
Germany

Journal for critical discussions in the multifaceted field of signal transduction mechanisms.

Laboratory Manual for Biomedical Research
United States

Provides protocols, animation tutorials, databases and pathways in biomedicine.

AJP - Endocrinology and Metabolism
United States

subsection of American Journal of Physiology. Current articles and archived articles are available.

Germany

Metabolic pathway analysis webservice, including shortest, alternate path and network analysis from Cologne University Bioinformatics Center, Germany.

BioBase
Germany

Biological databases, bioinformatics tools, and consulting in gene regulatory processes such as transcriptional control and signal transduction.

American Society for Bone and Mineral Research
United States

Scientific society composed of individuals actively involved in clinical and basic aspects of bone and mineral metabolism.

Integrative BioInformatics
United States

Integrative BioInformatics is a biotech consulting firm with expertise in computational biology. It specializes in bringing its software solutions to ...

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