Biology News
Biology's Sanjana Receives DARPA 2018 Young Faculty Award for Precise Gene Repair - NYU News (press release)


NYU News (press release)
“Over the past five years, CRISPR systems have made it relatively easy to knock-out or block expression of certain genes in human cells,” explains Sanjana, assistant professor in NYU's Department of Biology and Neuroscience and Physiology at NYU School ...

The European Marine Biological Resource Center becomes a European Research Innovation Centre - Science Business


Science Business
The European Center for Marine Biological Resources, EMBRC, has celebrated its adoption as a European Research Infrastructure Consortium (ERIC). The event took place at Sorbonne University, where the EMBRC headquarters are located, in the ...

Semi-Automated Imaging Technique for Cloned Cells, and Verification of Monoclonality - News-Medical.net


News-Medical.net
In cell biology research, it is vital that cell lines under study be monoclonal, proliferating from a single cell. This is important for all applications in this field, such as the production of knock-down cells or clones which highly express some ...

KORC : Knock Out Rat Consortium

Philadelphia, Pennsylvania - United States

The Knock Out Rat Consortium (KORC) is formed by individuals and institutions interested in the goal of creating knockout rats using multiple different technologies. Knockout rats can be used for functional genomics and also for drug discovery.

Mission Statement :

* The mission of the KORC is to create rats with single gene disruptions (knockouts) using all available technology.
* Our goal is create at least one rat with a null mutation corresponding to every gene in the rat genome.
* We will create all mutations on the same background strain of rat, namely Fischer.
* Each knockout will be bred into at least one male rat, which will be sacrificed for tissue collection and cryopreservation of sperm.
* Cryopreserved sperm can be used to create knockout rats with specific null mutations by the process called intracytoplasmic sperm injection (ICSI).

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