
Structural Biology Brussels (SBB)
Elsene - BelgiumWe unravel the 3D-structures of proteins. We explore the relationships between protein structure, function, and dynamics. We exploit our insights for the design of new medically relevant molecules. The Structural Biology Brussels Lab, headed by Jan Steyaert was founded by Lode Wyns in the seventies at the Vrije Universiteit Brussel and is part of one of the Flanders Institute for Biotechnology departments. Our dynamic and modern university is centrally situated in Brussels, the capital of Flanders, Belgium and Europe. The understanding of the function of a protein, from its structure to its dynamics, remains the central theme of the lab. Our multidisciplinary team of about 40 researchers is housed in new laboratory facilities and combines extensive expertise in biophysics and molecular biology. We master genetic engineering, protein purification, enzymology, calorimetry, crystallography, surface plasmon resonance, atomic force microscopy and now also NMR. Major research interests include Biomedical targets, Structural enzymology, Bacterial adhesion, Toxin-antitoxin systems and Biomolecular NMR. Translational research is intrinsic to our programs, with possible applications in medicine.
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Structural analysis of living material at every level of organization by all methods: light microscopy including confocal microscopy, electron microscopy, NMR, X-ray diffraction.
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Graduate program information, applications, departmental details, seminar schedules and research interests within the faculty at the University of Minnesota.
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Articles in all fields related to the cellular function of macromolecules as analyzed by the range biological, biophysical and biochemical techniques.
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Research on motility through cross-disciplinary research, profiles of team members, postdoctoral opportunities, job openings at Perdue University, West Lafayette, Indiana.
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Studies of the alpha helical cytokine family Interferon-gamma, interferon-alpha, and interleukin-10, their receptors, intracellular signaling molecules with emphasis on understanding the structural basis of molecular recognition events that subsequently lead to cellular signal transduction, maintained by Mark R. Walter laboratory at the University of Alabama at Birmingham.
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- Immunology
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SBC beamlines are well suited for a wide range of crystallographic experiments involving: - Crystals of macromolecular assemblies with very large unit cell - MAD/SAD phasing - Crystals of membrane proteins - Small, weakly diffracting crystals - Ultra-high resolution crystallography - Cryo-crystallography
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- Biochemistry and Molecular Biology
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