Biology News
Systems and Physiology lab, June 22nd, 2018 - BU Today


BU Today
Summer learning: Grace Shin (CAS'19) tries out a breathing mask during a lab on metabolism and respiratory volumes and capacities for her Systems and Physiology class on Thursday. Photo by Jackie Ricciardi ...

Nobel prize winning tech reveals herpes virus structure - Lab News


Lab News
The development of cryo-EM as a technique for resolving detailed atomic structures was developed at the MRC Laboratory of Molecular Biology. Dr Jonathan Pearce, Head of Infections and Immunity at the MRC, said: “Dr Bhella and his team's findings ...

UNDP, UN Environment, and the CBD Secretariat launch the UN Biodiversity Lab to revolutionize biodiversity planning ... - UNDP


UNDP
The UN Biodiversity Lab provides spatial data through a free, cloud-based tool to support Parties to the UN Convention on Biological Diversity (CBD) in reporting on their achievements and to inform their conservation decision making. National ...

The Friedman Lab: Nucleic Acids

Kansas City, Missouri - United States

Nucleic acids are fascinating. About every decade a new feature of their role in biology is uncovered. Initially it was as the repository of genetic information (genomic DNA). Then it was as the medium by which that information is converted into proteins (messenger and transfer RNA). Then it was as catalysts (ribozymes and the ribosome). And then, in spectacular fashion, it was as a parallel and previously unseen universe of genetic control (small interfering RNA and micro RNA). Nucleic acids are truly central to modern biology.

Chemistry has a unique and powerful contribution to make to the world of nucleic acids. These contributions include the synthesis of potential new drugs that target nucleic acids and their interfaces with proteins, the design of new probes that bind folded nucleic acids and the creation of new tools for controlling gene expression. Chemistry lets you look at a molecule and say "what would happen if I changed these atoms..." and then answer the question. Nucleic acids, as powerful and central as the are, are ultimately just molecules, and amendable to all the tools of the chemist. While we would never want to be completely defined by a specific label, the closest one that captures what we do is nucleic acids at the interface of chemistry and biology.

Related
Biochemistry of Nucleic Acids
United States

Lecture notes on nucleic acid structure, DNA replication and repair, the genetic code and translation, as well as cancer genes, from Oregon State University, USA 2003.

Nucleic Acids Research
United Kingdom

Publishes papers on methods, RNA, structural biology, surveys and summaries, molecular biology, enzymology, chemistry, and genome structure and mapping.

Chem4Kids.com: Nucleic Acids
United States

Offers a very brief introduction to the types of nucleic acids and their five basic building blocks: uracil, cytosine, thymine, adenine, and guanine.

United States

Provides an overview of their structure and nomenclature, adenosine and guanosine derivatives, the properties of DNA, and related topics.

Nucleic Acids Research
United States

Results of leading edge research into physical, chemical, biochemical and biological aspects of nucleic acids and proteins involved in nucleic acid metabolism and/or interactions.

Nucleic Acids in Drug Discovery
United States

Industry meeting stressing the importance of target validation and functional genomics tools, successful early research, and new applications of nucleic acids.

Nucleic Acids Symposium Series
United States

Supplementary publication to Nucleic Acids Research.

Unregulated Hazards 'Naked' and 'Free' Nucleic Acids
United Kingdom

Discusses the hazards associated with naked/free nucleic acids being produced in laboratories and released unregulated into the environment.

Abbreviations and Symbols for Nucleic Acids, Polynucleotides and their Constituents
United Kingdom

Web version of the recommendations set forth in 1970.

Germany

Archives from research in analysis, separation, synthesis, biosynthesis, analogues, derivatives, isotopes, radiated modifications, glycosylation, polyamines and peptides, Applications in medicine, food chemistry, nutrition, pharmacology, and roles in pathophysiology from Springer.